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Over 500 million people are affected by OA worldwide, leading to a global prevalence of around 7%. The forecast for OA is alarming; with an ageing population the prevalence is expected to rise dramatically in the coming decades.
OA can affect any joint and is most prevalent in the knee and hip, with hip OA leading to the greatest disability
Despite its tremendous burden, there is no curable treatment available and current strategies therefore focus on symptomatic treatment, with only modest effect. This is mainly due to a lack of knowledge on the etiology, pathophysiology and risk factors of hip OA. Still, some risk factors for hip OA have previously been identified on a group level such as age, gender, genetics, race and hip morphology. However, current cohort studies are underpowered to detect risk factors and predict the risk of hip OA on an individual level. The lack of knowledge on person specific risk factors for hip OA makes efficient and effective preventive and treatment strategies challenging, if not impossible.
We want to change the current ‘one size fits all’ management into person specific preventive and treatment strategies. This all starts with better knowledge on determinants and risk factors for hip OA. However, a lot of data is needed to create such personalized predictions for hip OA.
This is why we initiated the Worldwide Collaboration in OsteoArthritis prediCtion of the Hip: the World COACH consortium. This consortium includes all prospective cohort studies worldwide that have longitudinal (with at least 4 years apart) hip imaging data available (Figure 1).
Our aims are to better understand determinants and risk factors for development and progression of hip OA and to develop a person specific risk prediction model for hip OA.
With this knowledge, we hope to guide future person specific prevention and treatment strategies.
To study the research questions of the World COACH consortium, we created several work packages:
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Do you want to collaborate with the World COACH consortium? Do you have a research proposal for using the consortium database? Contact us!
